Investigation of NF-κB1 and NF-κBIA Gene Polymorphism in Non-Small Cell Lung Cancer

Table 3

Distribution of NF-κB1 and NF-κBIA genotypes with clinic features in NSCLC patients.

	NF-κB1				NF-κBIA
	II	ID	DD	𝑃 value	AA	AG	GG	𝑃 value
	𝑛 (%)	𝑛 (%)	𝑛 (%)		𝑛 (%)	𝑛 (%)	𝑛 (%)
Sex
Men	33 (37.10)	41 (46.10)	15 (16.80)	0.980	15 (16.90)	43 (48.30)	31 (34.80)	0.570
Women	2 (33.30)	3 (50.00)	1 (16.70)		2 (33.30)	2 (33.30)	2 (33.30)
Age
<57	10 (29.4)	17 (50)	7 (20.6)	0.496	5 (14.7)	19 (55.9)	10 (29.4)	0.567
≥57	27 (41.5)	27 (41.5)	11 (16.9)		12 (18.5)	29 (44.6)	24 (36.9)
Smoking (box/year)
<50	25 (48.10)	24 (46.20)	3 (5.80)	0.02	10 (19.20)	25 (48.10)	17 (32.70)	0.876
≥50	10 (23.30)	20 (46.50)	13 (30.20)		7 (16.30)	20 (46.50)	16 (37.20)
Alcohol consumption
No	17 (31.50)	28 (51.90)	9 (16.70)	0.405	6 (11.10)	31 (57.40)	17 (31.50)	0.044
Yes	18 (43.90)	16 (39.00)	7 (17.10)		11 (26.80)	14 (34.10)	16 (39.00)
Histopathology
Squamous	16 (45.70)	16 (45.70)	3 (8.60)	0.179	7 (20.00)	20 (57.10)	8 (22.90)	0.173
Nonsquamous	19 (31.70)	28 (46.70)	13 (21.70)		10 (16.70)	25 (41.70)	25 (41.70)
Total protein
<6 g/L	2 (50.00)	0 (0)	2 (50.00)	0.087	0 (0)	3 (75.00)	1 (25.00)	0.452
≥6 g/L	31 (38.30)	38 (46.90)	12 (14.80)		16 (19.80)	37 (45.70)	28 (34.60)
Albumin
<3 g/L	6 (54.50)	1 (9.10)	4 (36.40)	0.019	1 (9.10)	6 (54.50)	4 (36.40)	0.635
≥3 g/L	26 (34.70)	39 (52.00)	10 (13.30)		16 (21.30)	35 (46.70)	24 (32.00)
Calcium
<10 mg/Dl	30 (40.00)	30 (40.00)	15 (20.00)	0.001	16 (21.30)	35 (46.70)	24 (32.00)	0.506
≥10 mg/dL	0 (0)	11 (100)	0 (0)		1 (9.10)	7 (63.60)	3 (27.30)
LDH
<250 U/L	22 (36.10)	28 (45.90)	11 (18.00)	0.644	13 (21.30)	31 (50.80)	17 (27.90)	0.249
≥250 U/L	10 (47.60)	8 (38.10)	3 (14.30)		3 (14.30)	8 (38.10)	10 (47.60)