Research Article

TFIIB-Related Factor 2 Is Associated with Poor Prognosis of Nonsmall Cell Lung Cancer Patients through Promoting Tumor Epithelial-Mesenchymal Transition

Figure 5

Targeted knockdown of BRF2 expression inhibited the metastatic potentials of NSCLC A549 cells. (a): (A): the levels of BRF2 protein in the A549 cells separately treated with different siRNAs; (B): the detection of the knockdown of BRF2 in A549 cells by WB and RT-PCR, respectively ( ). (b) The representative pictures of wound healing assay (×200) and the quantitative analysis of the migration potential of A549 cells ( ). (c) Downregulation of BRF2 protein decreased the invasion of A549 cells Transwell invasion assay: (A) BRF2-siRNA A549 cells; (B) control-siRNA A549 cells; (C) A549 cells (×400); (D) the quantitative analysis of the invasion potential of A549 cells ( ).
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