Detection and Antibiotic Treatment of Mycoplasma arginini Contamination in a Mouse Epithelial Cell Line Restore Normal Cell Physiology

Figure 2

Example image of contaminated cells using oblique illumination. This image is of untreated cells, 18 d after plating. Plane of focus was set to the apical surface. Under normal viewing, cells appear healthy (no blebbing/apoptosis), while use of oblique illumination clearly shows the presence of bright punctate dots covering the apical membrane of many cells.