Detection and Antibiotic Treatment of Mycoplasma arginini Contamination in a Mouse Epithelial Cell Line Restore Normal Cell Physiology

Figure 5

DAPI counterstained image of contaminated cells. This fluorescence image acquired with a 100x/1.47 immersion lens shows the presence of mycoplasma contamination. Evidence for mycoplasma contamination is given by the presence of large multinucleate cells, tightly clumped groups of cells, and the presence of small extranuclear DNA stains.