Analgesic and Anti-Inflammatory Activities of Leaf Extract of Mallotus repandus (Willd.) Muell. Arg.

Table 2

Effects of various extracts of M. repandus on the latency time in tail immersion test.

Group	Doses (mg/kg)	Latency time(s)
		0 h	1 h	2 h	3 h	4 h
Control	1% Tween 80 in water (10 mL/kg)	4.462 ± 0.196	4.278 ± 0.370	4.404 ± 0.243	3.984 ± 0.334	3.936 ± 0.314
Pentazocine	10	4.18 ± 0.256	8.4 ± 0.51^*	8.294 ± 0.250^*	8.028 ± 0.96^*	6.834 ± 0.282^*
MLM	500	4.720 ± 0.343	5.540 ± 0.431	4.408 ± 0.556	5.138 ± 0.186	5.704 ± 0.639
	1000	4.314 ± 0.136	5.990 ± 1.297	4.164 ± 0.468	5.058 ± 0.403	4.742 ± 0.511
	2000	4.778 ± 0.133	7.720 ± 1.136	6.250 ± 1.625^*	7.540 ± 1.282^*	6.080 ± 0.460^*

Values are presented in mean ± SEM (). was considered statistically significant when compared against control. Overall time effect is considered extremely significant with (4, 80) = 5.910 and . Repeated measure ANOVA with Dunnet’s multiple comparison was performed to analyze this data set.