Research Article

-Mangostin Suppresses the Viability and Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells by Downregulating the PI3K/Akt Pathway

Figure 1

Treatment of pancreatic cancer cells with α-mangostin results in loss of cell viability. Pancreatic cancer BxPc-3 (a), Panc-1 (b), and hTERT-HPNE (c) cells were treated with α-mangostin at the indicated concentrations for 6, 12, 24, and 48 h. Cell viability relative to control was assessed using the MTT assay.
546353.fig.001a
(a)
546353.fig.001b
(b)
546353.fig.001c
(c)