Antiangiogenesis Therapy of Endometriosis Using PAMAM as a Gene Vector in a Noninvasive Animal Model

Table 6

Numbers of MVD (CD31-stained vessels per ×400 magnification) and VEGF 𝐻 score (per ×400 magnification) in endometriosis lesions in nude mice (mean ± SD).

Group	MVD	VEGF 𝐻 score
(1) HD PAMAM-Es	3.8±2.4^a	3.8±3.1
(2) LD PAMAM-Es	10.5±3.9	4.7±2.6
(3) Lipofectamine-Es	11.4±4.7	5.2±3.2
(4) PAMAM	11.9±6.7^a	7.0±3.1
(5) PBS	12.1±4.3^a	8.1±2.3

aStatistic significant difference between Group 1 and Group 4 and Group 5.