NGF Accelerates Cutaneous Wound Healing by Promoting the Migration of Dermal Fibroblasts via the PI3K/Akt-Rac1-JNK and ERK Pathways
Figure 2
Histological structure of wounded skin sections. (a) Hematoxylin and eosin stainingof wound healing at 14 days after wounding (×40). As compared with saline-treated control, epithelial crawling (the distance between two black arrows as indicated) in NGF-treated wounds advanced more rapidly, and more granulation tissue was found in the NGF-treated wound. (b) Masson’s trichrome staining of the wounded skin sections with saline or NGF treatment for 3 and 21 days after wounding (×200). There is a mild increase of collagen content (green) in NGF-treated wound tissue compared with saline-treated controls at different times after wounding.
