Loss of Microstructural Integrity in the Limbic-Subcortical Networks for Acute Symptomatic Traumatic Brain Injury

Table 2

Gray matter regions of significant FA reductions in 12 sTBI.

	Talairach			𝑡	Voxels
	𝑥	𝑦	𝑧	Value
Caudate head
L	−13	20	−1	2.40	128
Claustrum
L	−31	3	7	2.88	31
R	36	−8	6	3.00	34
Insula
L	−36	0	10	2.24	39
R	34	20	5	3.31	50
Putamen
L	−25	−3	−2	3.24	138
R	23	−1	3	3.30	176
Thalamus
L	−10	−8	15	2.99	297
R	15	−30	2	4.03	282
AN_Thalamus
L	−10	−9	14	2.55	45
R	10	−6	13	2.79	61
MDN_Thalamus
L	−7	−20	7	2.66	204
R	12	−19	6	3.65	184
Pulvinar_Thalamus
L	−5	−23	9	2.92	166
R	17	−24	6	3.38	301
VLN_Thalamus
L	−9	−8	6	1.96	67
R	11	−11	−17	2.47	66
sACC BA 25
L	−7	17	−10	2.14	30
R	8	17	−10	2.20	47
pACC BA 32
L	−12	36	17	3.67	71
R	10	37	19	2.96	80
Cigulate cortex BA 32/24
L	−7	−7	39	2.23	218
R	9	−2	47	4.93	326
Amygdala
L	−28	−6	−12	1.64	28
PH BA 36/37
L	−23	−30	−12	3.84	185
R	23	−30	−4	3.14	143
PCC BA 23
L	−1	−56	15	1.60	26
R	5	−47	24	3.37	199
OFC BA 10/47
L	−10	−13	49	4.38	112
DLPFC BA 6/9
L	−10	−13	49	4.38	112
R	5	−22	50	3.14	82
Lingual gyrus BA 18/19
L	−17	−64	0	2.51	86
R	13	−52	3	3.45	149
Fusiform gyrus BA 37/20
L	−44	−39	−17	2.36	45
R	32	−36	−17	1.27	24
R	20	−42	−7	1.39	21

AsTBI: symptomatic traumatic brain injury; LN: lentiform nucleus; AN: anterior nucleus; MDN: medial dorsal nucleus; VLN: ventral lateral nucleus; sACC: subgenual anterior cingulate cortex; pACC: perigenual anterior cingulate cortex; PH: parahippocampal gyrus; PCC: posterior cingulate cortex; OFC: orbitofrontal cortex; DLPFC: dorsolateral prefrontal cortex; BA: Brodmann area; PH: parahippocampus; AL: anterior lobe.