Experience of Preimplantation Genetic Diagnosis with HLA Matching at the University Hospital Virgen del Rocío in Spain: Technical and Clinical Overview

Table 2

Clinical data for preimplantational HLA typing at HUVR.

	HLA + PGD	HLA-only	Total
No of couples treated	5	2	7
Maternal age	31.0±2.4	28.0±2.8	30.1±2.7
No of cycles performed	21	5	26
No of cycles performed per couple	4.2±2.9	2.5±0.7	3.7±2.6
No of oocytes retrieved	391	104	495
No of oocytes retrieved per cycle	18.6±7.0	16.3±9.0	17.9±7.6
No of mature oocytes submitted to ICSI	305	77	382
% of oocytes injected	78.0%	74.0%	77.2%
No of mature oocytes submitted to ICSI per cycle	14.6±6.5	13.1±9.3	14.2±7.3
No of oocytes fertilized	182	47	229
% of oocytes fertilized	59.7%	61.0%	59.9%
No of oocytes fertilized per cycle	8.7±3.9	7.3±5.5	8.3±4.4
No of embryos analyzed	160	42	202
% of embryos analyzed	87.9%	89.4%	88.2%
No of embryos analyzed per cycle	7.6±3.8	6.2±6.4	7.2±4.6
No of transfers	5	2	7
% of transfers	23.8%	40%	26.9%
No of embryos transferred	6	3	9
No of pregnancies	2	1	3
No of clinical pregnancies	1	1	2
No of clinical pregnancies per cycle	4.8%	20%	7.7%
No of clinical pregnancies per transfer	20%	50%	28.6%
No of embryos implanted	2	1	3
Implantation rate	33.3%	33.3%	33.3%
No of pregnancies went to term	1	1	2
No of babies born	1	1	2
Live birth rate per cycle	4.8%	20%	7.7%