Experience of Preimplantation Genetic Diagnosis with HLA Matching at the University Hospital Virgen del Rocío in Spain: Technical and Clinical Overview

Table 3

Comparison of the clinical data for preimplantational HLA typing at different Centres.

	Reproductive Genetics Institute Chicago (Rechitsky et al., 2004) [7]	UZ Brussel (Van de Velde et al., 2009) [12]	Genoma (Van de Velde et al., 2009) [12]	Istanbul Memorial Hospital’s (Kahraman et al., 2011) [9]	HUVR, Spain (this work)
No of couples treated	26	32	107	171	7
No of cycles performed	46	85	199	327	26
% of oocytes injected	NA	82.7%	76.8%	NA	77.2%
% of oocytes fertilized	NA	68.0%	88.5%	NA	59.9%
% of embryos analyzed	NA	40.3%	76.5%	NA	88.2%
% of embryos diagnosed	93.0%	99.1%	94.2%	92.0%	96.0%
No of transfers	33	27	138	NA	7
% of transfers	71.7%	31.8%	69.3%	64.8%	26.9%
No of embryos transferred	50	34	216	NA	9
No of clinical pregnancies	6	9	48	NA	2
% of clinical pregnancies per cycle	13.0%	10.6%	24.1%	NA	7.7%
% of clinical pregnancies per transfer	18.2%	33.3%	34.8%	34.9%	28.6%
Implantation rate	12.0%	32.4%	28.7%	26.3%	33.3%
No of pregnancies went to term	5	8	37	52	2
Live birth rate per cycle	10.9%	9.4%	18.6%	15.9%	7.7%