Synergistic Effect and Antiquorum Sensing Activity of Nymphaea tetragona (Water Lily) Extract

Table 5

Quorum sensing inhibition activity (as pigment inhibition zone diameters) of Nymphaea tetragona 50% methanol extract and solvent fractions of the crude extract against C. violaceum.

Solvent fraction/antibiotic	Concentration	Pigment inhibition diameter (mm)
	(𝜇g/disk)	Mean ± SD
Tetracycline	10	16.33±0.58^∗
Furanone	100	16.67±0.58^a
Normal Saline	—	ND
NTME	600	13.67±1.15^c
DFNTE	600	13.33±0.58^c
EFNTE	600	14.67±1.15^b
BFNTE	600	14.33±1.53^b

NTME: N. tetragona 50% methanol extract, DFNTE: dichloromethane fraction of N. tetragona 50% methanol extract, EFNTE: ethyl acetate fraction of N. tetragona 50% methanol extract, BFNTE: butanol fraction of N. tetragona 50% methanol extract. *Diameter of clear zone. ND: no activity detected. Data shown represent the mean ± SD of three replicates. Different alphabets indicate significant difference.