Research Article
Meta-Analysis of Low Density Lipoprotein Receptor (LDLR) rs2228671 Polymorphism and Coronary Heart Disease
Table 1
Characteristics of the association studies between rs2228671 and CHD.
| Author and year | Ethnic group | Genotype (CC/CT/TT) | -allele | Cases | Controls |
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Ortlepp et al. (2003) [11] | German | 937/216/10 | 972/255/22 | 0.0453 | Krawczak et al. (2006) [12] | German | 1755/379/19 | 1840/474/25 | 0.0184 | Samani et al. (2007) [13] | German | 781/93/1 | 1417/224/3 | 0.0281 | Samani et al. (2007) [13] | British | 1578/322/13 | 2332/569/34 | 0.0051 | Schunkert et al. (2008) [14] | German | 236/43/2 | 224/61/5 | 0.0343 | Erdmann et al. (2009) [15] | German | 282/64/3 | 671/164/15 | 0.3333 | Martinelli et al. (2010) [16] | Italian | 549/134/9 | 227/61/3 | 0.73 | Our study (2013) | Chinese | 157/4/1 | 111/2/0 | 0.485 |
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