Iminoflavones Combat 1,2-Dimethyl Hydrazine-Induced Aberrant Crypt Foci Development in Colon Cancer

Table 3

Effect on ACF incidence, number of ACFs, and size of polyps (adenomas) in DMH-induced colon cancer in rats.

Groups	ACF incidence (%)	Polyps (adenomas)
		Number of ACFs/cm^2; (mean ± SEM)	Small; (0.1–1 mm)	Medium; (2–4 mm)	Large; (5–8 mm)	Total; count
Control	0	0	0	0	0	0
DMH	100.0	16.85 ± 1.5^a	4	5	4	13
5-FU	100.0	11.6 ± 1.0^a	3	3	1	7
IMF-8	100.0	12.5 ± 1.6^a	4	5	0	8

Values are reported as mean ± SEM of three readings in triplicate.
^a𝑃<0.01 when compared to the control group.