Antidiabetic Activity of Acacia tortilis (Forsk.) Hayne ssp. raddiana Polysaccharide on Streptozotocin-Nicotinamide Induced Diabetic Rats

Table 1

Effect of AEATP on fasting insulin level (ng/mL) in type-2 diabetic Wistar rats.

Fasting insulin level (ng/mL)	Control	Diabetic control	Glimepiride treated	250 mg/kg of AEATP	500 mg/kg of AEATP	1000 mg/kg of AEATP
Basal	0.776 ± 0.026	0.803 ± 0.041	0.783 ± 0.041	0.830 ± 0.035	0.790 ± 0.049	0.803 ± 0.067
28th day	0.820 ± 0.024	0.373 ± 0.026^a#	0.723 ± 0.024^b#	0.550 ± 0.024^b#	0.613 ± 0.020^b#	0.683 ± 0.024^b#, c‡

Each group (𝑛=6) represents mean ± standard error of means. Data was analyzed by using one-way ANOVA followed by Tukey’s multiple test; a control, b diabetic control, c 500 mg/kg of AEATP. ^∗𝑃<0.0001, ^#𝑃<0.001, ^†𝑃<0.01, ^‡𝑃<0.05.