Research Article

Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency

Figure 2

BrdU incorporation. Green represents BrdU-positive cells, red represents cells positive for nestin (a specific marker of HPCs), and blue represents nuclei stained with Hoechst. (c) Analysis of the TD group; the proportion of BrdU-positive cells of TD (a2) was significantly lower than that of the control group (a1). (d) Analysis of the oxythiamine-added groups; the proportion of BrdU-positive cells in HPCs treated with 50 μM/L (b2) and 100 μM/L (b3) oxythiamine was significantly lower than that of the 0 μM/L group (b1). (a1) and (a2): scale = 50 μm; (b1), (b2), and (b3): scale = 100 μm.
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