Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency

<table>Inhibition of the proliferation of HPCs by oxythiamine. The number of neurospheres significantly decreased in a dose-dependent manner in HPCs treated with &gt;5 <i>μ</i>M/L oxythiamine ((a1)–(a5), (c)), and the proportion of small neurospheres was in direct proportion to the oxythiamine dose (d). The OD values generated by the CCK-8 assay of HPCs treated with oxythiamine at doses &gt;5 <i>μ</i>M/L were significantly lower than those of the 0 <i>μ</i>M/L group (b). Scale = 100 <i>μ</i>m.</table>

BioMed Research International

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Figure 3: Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency 

Figure 3 | Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency 