Xanthium strumarium L. Extracts Produce DNA Damage Mediated by Cytotoxicity in In Vitro Assays but Does Not Induce Micronucleus in Mice
Figure 2
SCE assay analysis in CHO cells treated with crude extract of X. strumarium L. (2, 5 and 15 μg/mL). Cells were exposed for 3 h or 27 h to X. strumarium extracts. Cultures received BrdUrd at the final concentration of 1.5 μg/mL during the last 24 h of incubation. Negative control: DMSO (1%). Each value represents the mean ± SD of three independent experiments. Statistically significant difference compared to negative control (*, ANOVA and Dunnett’s test).
