Research Article

Impact of Core-Forming Segment Structure on Drug Loading in Biodegradable Polymeric Micelles Using PEG-b-Poly(lactide-co-depsipeptide) Block Copolymers

Table 3

Characterization of micelles versus drugs in 30% feed.

DrugaDrug loading (DL) (wt%)
b-PLLAb-PDLLAb-PLGL b-PLGF

Fluorescein16.620.029.026.2
4-Aminofluorescein3.04.77.37.2
Pyrene0.50.60.60.7
Doxorubicin30.328.629.729.8

DL (%) = (drug found)/(micelle found) (w/w) 100.
The amount of drug in feed = 30 wt%.