Oral and Intraperitoneal Administration of Quercetin Decreased Lymphocyte DNA Damage and Plasma Lipid Peroxidation Induced by TSA In Vivo
Figure 1
Effects of trichostatin A (TSA) alone or in combination with quercetin on tumor growth in tumor-bearing mice. Thirty-six male nude mice were injected with A549 cells and after 3 weeks were treated with TSA alone (0.5 mg/kg body weight) or in combination with quercetin (OL and OH, quercetin administered orally at 20 and 100 mg/kg body weight, resp.; IL and IH, quercetin administered intraperitoneally at 2 and 10 mg/kg body weight, resp.) for 16 weeks as described in Section 2. The control group was administered the vehicle only. Values (means ± SD, ) with a denote a significant different from the control group, while a # is significantly different from the TSA group ().
