Molecular Epidemiology and Genotyping of Mycobacterium tuberculosis Isolated in Baghdad

Table 4

Description of clusters containing 5 or more isolates in this study and their worldwide distribution in the SITVIT2 database.

SIT (lineage) octal number; Spoligotype description	Number (%) in study	% in study versus database	Distribution in regions with ≥3% of a given SIT*	Distribution in countries with ≥3% of a given SIT**
	8 (2.96)	10.26	ASIA-W 65.39, ASIA-S 12.82, AFRI-E 7.69, EURO-N 5.13, EURO-W 3.85	SAU 38.46, IRQ 25.64, IRN 7.69, TZA 3.85
	10 (3.7)	1.77	AFRI-E 26.68, ASIA-W 22.26, AFRI-N 14.84, ASIA-S 13.6, AMER-N 9.19, EURO-N 4.95, EURO-W 4.77	ETH 25.44, SAU 16.61, SDN 12.19, USA 9.19, IND 8.66, IRQ 5.12, IRN 3.0
	12 (4.44)	0.87	ASIA-S 54.08, AMER-N 15.81, ASIA-W 7.51, EURO-W 6.14, AFRI-E 5.13, EURO-N 4.19, EURO-S 3.61	IND 33.0, USA 15.81, PAK 10.4, SAU 5.63, BGD 5.42, IRN 4.48, ITA 3.47, NLD 3.11, ETH 3.11
	6 (2.22)	0.18	AMER-S 18.03, EURO-W 17.88, AMER-N 17.88, EURO-S 11.75, EURO-E 5.62, EURO-N 4.36, AFRI-N 4.33, AFRI-S 4.12, CARI 3.55, ASIA-W 3.19	USA 17.85, BRA 7.18, FXX 7.0, AUT 6.19, ITA 5.53, ESP 5.53, PER 4.81, ZAF 4.12, CZE 3.73
	5 (1.85)	0.08	EURO-W 16.17, AMER-N 13.93, AMER-S 12.43, EURO-S 9.72, ASIA-W 7.19, EURO-N 5.51, AFRI-S 5.13, AFRI-E 4.66, ASIA-E 4.38, AFRI-N 3.64, EURO-E 3.37, AMER-C 3.34	USA 13.64, FXX 8.14, ITA 5.51, BRA 5.3, ZAF 5.02, TUR 3.59, AUT 3.54, CHN 3.19
	8 (2.96)	3.31	ASIA-W 16.53, ASIA-S 15.29, ASIA-E 15.29, AFRI-N 14.88, AMER-N 8.26, AFRI-S 6.61, ASIA-N 4.13, AMER-S 3.72	CHN 15.29, IND 14.46, EGY 14.05, USA 8.26, SAU 8.26, ZAF 6.61, IRQ 5.79, RUS 4.13
	6 (2.22)	8.7	AMER-S 18.84, ASIA-W 15.94, EURO-W 11.59, ASIA-S 10.15, EURO-S 7.25, AMER-N 7.25, AFRI-M 7.25, AFRI-E 5.8, EURO-E 4.35, CARI 4.35, AFRI-W 4.35	IRN 10.15, FXX 10.15, BRA 10.15, IRQ 8.7, USA 7.25, CMR 7.25, TUR 4.35, MDG 4.35, GUF 4.35, ARG 4.35
	6 (2.22)	3.9	ASIA-W 18.83, EURO-W 17.53, AMER-S 13.64, EURO-S 9.74, ASIA-E 9.74, AMER-N 5.2, AFRI-E 5.2, EURO-E 4.55, AMER-C 4.55	FXX 15.58, TUR 12.34, ITA 6.49, VEN 5.84, CHN 5.84, USA 5.2, MOZ 4.55, JPN 3.9, IRQ 3.9, CZE 3.9, BRA 3.9, MEX 3.25, ARG 3.25
	6 (2.22)	3.08	ASIA-S 54.36, EURO-W 16.41, ASIA-W 11.8, EURO-N 5.64, ASIA-E 5.13	IRN 49.23, NLD 7.69, SAU 6.15, IRQ 5.13, CHN 5.13, SWE 4.62, AUT 4.62, DEU 3.59
	9 (3.33)	28.13	ASIA-S 37.5, ASIA-W 31.25, EURO-W 12.5, AMER-N 12.5, ASIA-SE 3.13, AFRI-E 3.13	IND 34.38, IRQ 28.13, USA 12.5, FXX 9.38, SAU 3.13, PAK 3.13, NLD 3.13, MOZ 3.13, MMR 3.13
	9 (3.33)	5.11	ASIA-W 42.61, EURO-E 22.73, EURO-W 15.91, EURO-N 7.39, EURO-S 3.41	BGR 22.73, TUR 19.89, SAU 13.07, IRQ 9.09, SWE 6.25, AUT 5.68, FXX 3.41
	17 (6.3)	80.95	ASIA-W 85.71, AFRI-M 9.52, AFRI-E 4.76	IRQ 80.95, CAF 9.52, SAU 4.76, ETH 4.76
	17 (6.3)	41.46	ASIA-W 90.24, AMER-N 4.88	IRQ 90.24, USA 4.88
	11 (4.07)	100	ASIA-W 100.0	IRQ 100.0
	8 (2.96)	100	ASIA-W 100.0	IRQ 100.0

∗Worldwide distribution is reported for regions with more than 3% of a given SITs as compared to their total number in the SITVIT2 database. The definition of macrogeographical regions and subregions (http://unstats.un.org/unsd/methods/m49/m49regin.htm) is according to the United Nations; regions: AFRI (Africa), AMER (Americas), ASIA (Asia), EURO (Europe), and OCE (Oceania) are subdivided in E (eastern), M (middle), C (central), N (northern), S (southern), SE (south eastern), and W (western). Furthermore, CARIB (caribbean) belongs to Americas, while Oceania is subdivided in 4 subregions, AUST (Australasia), MEL (Melanesia), MIC (Micronesia), and POLY (Polynesia). Note that in our classification scheme, Russia has been attributed a new subregion by itself (northern Asia) instead of including it among the rest of eastern Europe. It reflects its geographical localization as well as due to the similarity of specific TB genotypes circulating in Russia (a majority of Beijing genotypes) with those prevalent in central, eastern, and south eastern Asia.
**The 3 letter country codes are according to http://en.wikipedia.org/wiki/ISO_3166-1_alpha-3; countrywide distribution is only shown for SITs with ≥3% of a given SITs as compared to their total number in the SITVIT2 database.