Antimicrobial Activity of Coronarin D and Its Synergistic Potential with Antibiotics

Table 1

Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values (𝜇g/mL) of antibiotics and coronarin D against Gram-positive and Gram-negative bacteria.

	MIC and MBC of coronarin D and antibiotics against tested bacteria (𝜇g/mL)
	E. coli	P. aeruginosa	S. typhimurium	S. aureus	S. epidermidis	E. faecalis	B. cereus
MIC of coronarin D	>200	>200	>200	12.5	12.5	50	6.25
MBC of coronarin D	—	—	—	25	50	100	12.5
MIC of oxacillin	—	—	—	1.56	0.78	12.5	25
MBC of oxacillin	—	—	—	2.34	1.56	12.5	37.5
MIC of gentamicin	1.56	1.56	0.78	3.12	0.78	12.5	0.39
MBC of gentamicin	3.12	3.12	1.56	6.25	1.56	12.5	0.78
MIC of ciprofloxacin	2.34	0.39	0.39	0.195	0.39	1.56	0.39
MBC of ciprofloxacin	3.12	0.78	0.78	0.195	0.39	3.12	0.78

(—) means not test.