Informative Gene Selection and Direct Classification of Tumor Based on Chi-Square Test of Pairwise Gene Interactions
Table 5
Test accuracy of different classifiers with informative genes selected by different feature-selection methods.
Classifier
Feature-selection method
Leuk1
Lung1
Leuk2
SRBCT
Breast
Lung2
DLBCL
Leuk3
Cancers
GCM
Aver-
NB
ALL*
85.29
81.25
100.00
60.00
66.67
88.06
86.67
32.14
79.73
52.17
73.20
-IRG-DC
97.06
81.25
100.00
85.00
86.67
92.54
96.67
59.82
82.43
60.87
84.23
mRMR
79.41
68.75
100.00
90.00
93.33
97.01
96.67
74.11
70.27
45.65
81.52
SVM-RFE
67.65
81.25
80.00
95.00
80.00
89.55
90.00
95.00
77.03
63.04
81.85
HC-K-TSP
91.18
81.25
100.00
80.00
80.00
95.52
86.67
100.00
77.03
65.22
85.69
TSG
91.18
84.38
93.33
100
86.67
94.03
100
51.79
71.62
65.22
83.82
Aver-†
85.30
79.38
94.67
90.00
85.33
93.73
94
76.14
75.68
60.00
83.42
KNN
ALL*
67.65
75.00
86.67
70.00‡
63.33
88.06
93.33
75.89
64.86
34.78
71.96
-IRG-DC
97.06
71.88
86.67
100.00
86.67
85.07
96.67
87.50
85.14
58.70
85.54
mRMR
70.59
68.75
80.00
80.00
96.67
86.57
100.00
91.07
54.05
36.96
76.47
SVM-RFE
76.47
68.75
86.67
100.00
90.00
86.57
90.00
91.96
58.11
45.65
79.42
HC-K-TSP
88.24
87.50
86.67
85.00
83.33
94.03
93.33
88.39
64.86
52.17
82.35
TSG
91.18
75
93.33
100
80
88.06
96.67
86.6
74.32
39.13
82.43
Aver-†
84.71
74.38
86.67
93.00
87.33
88.06
95.33
89.10
67.30
46.52
81.24
SVM
ALL*
79.41
87.50
100.00
100.00
83.33
97.01
100.00
84.82
83.78
65.22
88.11
-IRG-DC
97.06
87.50
93.33
100.00
93.33
92.54
96.67
86.61
91.89
56.52
89.54
mRMR
76.47
78.13
100.00
75.00
96.67
95.52
96.67
91.96
71.62
45.65
82.77
SVM-RFE
85.29
78.13
93.33
95.00
90.00
88.06
90.00
91.07
93.24
63.04
86.72
HC-K-TSP
85.29
84.38
100.00
90.00
86.67
98.51
96.67
94.64
82.43
60.87
87.95
TSG
91.18
81.25
93.33
80
80
94.03
100
80.36
68.92
54.35
82.34
Aver-†
87.06
81.88
96.00
88.00
89.33
93.73
96.00
88.93
81.62
56.09
85.86
-DC
-IRG-DC
97.06
84.38
100.00
100.00
90.00
97.01
93.33
93.75
85.14
67.39
90.81
mRMR
82.35
65.63
100.00
90.00
90.00
95.52
70.00
96.43
60.81
47.83
79.86
SVM-RFE
79.41
56.25
66.67
85.00
76.67
92.54
80.00
96.43
94.59
69.57
79.71
HC-K-TSP
97.06
84.38
100.00
95.00
76.67
97.01
93.33
88.39
78.38
69.57
87.98
TSG
97.06
81.25
100
100
86.67
95.52
93.33
91.07
79.73
67.39
89.20
Aver-†
90.59
74.38
93.33
94.00
84.00
95.52
86.00
93.21
79.73
64.35
85.51
Results reported in [28]; ‡30 in original paper, whereas the actual number was 70 after validation; †Aver- was the average accuracy of a classifier with informative genes selected by four feature-selection methods.