Efficacy of Intrauterine Device in the Treatment of Intrauterine Adhesions

Table 3

Summary of previously published studies that used various techniques of IUD therapy and ancillary treatment in patients with intrauterine adhesions.

Source, year	Type of IUD	Duration of IUD used	Hormone therapy	Foley; catheter	Hyaluronic acid	Amnion graft
Caspi and Perpinial, 1975 [30]	Lippes loop	3 cycles	Yes	No	No	No
March and Israel, 1976 [31]	Lippes loop	2 months	Yes	Yes	No	No
March and Israel, 1981 [37]	Lippes loop	2 months	Yes	Yes	No	No
Ismajovich et al., 1985 [43]	NR	3 months	No	No	No	No
Fedele et al., 1986 [40]	NR	3 months	Yes	No	No	No
Valle and Sciarra, 1988 [8]	NR	3 months	Yes	No	No	No
Bellingham, 1996 [42]	Copper	3 months	Yes	No	No	No
Roge et al., 1997 [9]	NR	3 months	Yes	Yes	No	No
Chen et al., 1997 [18]	Multiload Cu 375	2 weeks	Yes	No	No	No
Feng et al., 1999 [13]	Multiload Cu 375	3 months	Yes	No	No	No
Ozumba and Ezegwui, 2002 [32]	Lippes loop	3 cycles	Yes	No	No	No
Orhue et al., 2003 [19]	Lippes loop	3 cycles	Yes	Yes	No	No
Alborzi et al., 2003 [11]	NR	1 month	Yes	No	No	No
Zikopoulos et al., 2004 [16]	Multiload Cu 375	1 month	Yes	No	No	No
Efetie, 2006 [12]	Lippes loop	3 months	Yes	No	No	No
Shokeir et al., 2008 [41]	NR	3 months	Yes	No	No	No
Yasmin et al., 2007 [33]	Lippes loop	3 cycles	Yes	Yes	No	No
Yu et al., 2008 [7]	Cu T	3 months	Yes	No	No	No
Pabuccu et al., 2008 [28]	Lippes loop	2 months	Yes	No	No	No
Roy et al., 2010 [29]	Cu T	30 days	Yes	No	No	No
Salma et al., 2011 [34]	Uterine-shaped	1 month	Yes	Yes	Yes	No
Myers and Hurst, 2012 [35]	Copper	4–10 weeks	Yes	Yes	No	No
Mohamed et al., 2012 [39]	Copper T 380A	1–3 months	Yes	Yes	No	Yes
Yamamoto and Takeuchi, 2013 [36]	NR	2 cycles	Yes	No	No	No
Lin et al., 2013 [27]	Copper coil	2 months	Yes	Yes	Yes	No
Şendağ et al., 2013 [38]	Cu T	1–3 months	Yes	Yes	No	No

NR = not reported. IUD = intrauterine device. “Yes” = studies that used IUD. “No” = studies that did not use IUD.