Research Article

Depletion of Arginine by Recombinant Arginine Deiminase Induces nNOS-Activated Neurotoxicity in Neuroblastoma Cells

Figure 4

Effect of rADI on cell viability in NMDA-treated SH-SY5Y cells. The differentiated cells were incubated with control, 1 mM NMDA, 1 mU/mL rADI, cotreatment with NMDA and rADI, or cotreatment with arginine replenishment for 24 h. Cell viability was measured using the MTT assay. The error bars represent the SEM ( ). versus control; arg: arginine.
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