Depletion of Arginine by Recombinant Arginine Deiminase Induces nNOS-Activated Neurotoxicity in Neuroblastoma Cells
Figure 4
Effect of rADI on cell viability in NMDA-treated SH-SY5Y cells. The differentiated cells were incubated with control, 1 mM NMDA, 1 mU/mL rADI, cotreatment with NMDA and rADI, or cotreatment with arginine replenishment for 24 h. Cell viability was measured using the MTT assay. The error bars represent the SEM (). versus control; arg: arginine.