Identification of MicroRNA as Sepsis Biomarker Based on miRNAs Regulatory Network Analysis

Table 2

Candidate miRNAs with outlier activity in sepsis.

MicroRNA name (Hsa-)	Accession number (MIMAT)	𝑃 value (sepsis patients versus controls)	Fold change (log2)	NOD value	𝑃 value (NOD statistical significant value)	AUC value (95% CI)
let-7b	0000063	0.020	85.93	53	2.4𝐸−07	0.81
miR-16	0000069	0.030	55.79	35	3.12𝐸−07	0.84
miR-15b	0000417	0.001	192.07	33	3.82𝐸−07	0.95
miR-146a	0000449	0.002	−6.89	20	1.84𝐸−05	0.90
miR-210	0000267	0.023	1.64	15	0.0006	0.97
miR-340	0004692	0.021	−1.18	11	0.0021	0.88
miR-145	0000437	0.021	13.03	11	0.0021	0.83
miR-484	0002174	0.002	3.74	11	0.0021	0.92
miR-324-3p	0000762	0.021	2.45	10	0.0041	0.84
miR-486-5p	0002177	0.019	102.49	8	0.0151	0.97