Isolation and Biochemical Characterization of a New Thrombin-Like Serine Protease from Bothrops pirajai Snake Venom

Table 2

Comparison between thrombin and BpirSP-39 activities*.

Activities	Thrombin	BpirSP-39
Aggregation of platelet disaggregation	+	Not tested
Clot retraction	+	Not tested
Fibrinogen clotting	+	+
Factor XIII activation	+	+
Degradation of fibrinogen (𝛼 and 𝛽)	+	+
Hydrolysis of BAPNA	+	+
Inhibition by heparin	+	−
Inhibition by PMSF	+	+
Inhibition by citrate	+	−
Inhibition by EDTA	+	−

∗Adapted from Niewiarowski et al., 1979 [61].
The presented data represents a summary of thrombin and BpirSP-39 activities.