Review Article
Endothelial Dysfunction in Experimental Models of Arterial Hypertension: Cause or Consequence?
Table 1
Classification of endothelial dysfunction proposed by Evora [
55]. For more details and explanation see the original article.
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Endothelial dysfunction classification | | (I) Etiological classification | | (A) Primary or “genotypic”: demonstrated for example in normotensive patients with familial antecedents of essential arterial hypertension. | | (B) Secondary or “phenotypic”: present for example in cardiovascular diseases including arterial hypertension. | | (II) Functional classification | | (A) “Vasotonic”: implying a risk of vasospasm and thrombosis. | | (B) “Vasoplegic”: associated with a pathological release of endothelium-derived relaxing factors. | | (III) Evolutionary or prognostic classification | | (A) Reversible | | (B) Partially reversible | | (C) Irreversible | |
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