Research Article

Propofol Protects the Immature Rabbit Heart against Ischemia and Reperfusion Injury: Impact on Functional Recovery and Histopathological Changes

Figure 3

Histopathological assessment using light microscopy following ischemia and reperfusion. Light microscopy examination stained with toluidine blue (upper: control, middle: 2 μg/mL of propofol, and lower: 10 μg/mL of propofol). Myocardium with 2 μg/mL of propofol showed mild intracellular swelling and clumping of nuclear chromatin, whilst these changes were more evident in myocardium with 0 and 10 μg/mL of propofol. Interstitial (extracellular) edema was also less in 2 μg/mL than in 0 and 10 μg/mL.
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