Clinical Study

The Association of Long-Functioning Hemodialysis Vascular Access with Prevalence of Left Ventricular Hypertrophy in Kidney Transplant Recipients

Table 1

Characteristics of study patients with or without functioning vascular access (VA).

Patent VA ( )No patent VA ( )Statistical significance

Demographic and anthropometric data
 Age (years)49 (46–52)50 (48–52)0.58
 Gender (M/F)42/2556/390.88
 BMI (kg/m2)27.2 (26.0–28.4)26.7 (25.6–27.7)0.51
 BSA (m2)1.93 (1.88–1.99)1.88 (1.84–1.93)0.15
Past medical history
 Duration of pretransplant dialysis therapy (years)2.2 (1.9–2.8)2.5 (2.1–2.9)0.54
 Time after transplantation (years)8.0 (7.6–8.5)8.7 (8.3–9.1)0.08
 Duration of hypertension therapy (years)15.9 (14.3–17.5)17.3 (15.6–18.9)0.56
 Hypertension (n (%))55 (82.9)83 (87.4) 0.35
 Diabetes (n (%))17 (25.4)20 (21.1)0.52
 Symptomatic coronary artery disease (n (%))12 (17.9)16 (16.8)0.97
 MACE (n (%))12 (17.9)13 (13.7)0.46
 Active smokers (n (%)) 12 (17.9)20 (21.1)0.62
Kidney graft function
 eGFR-MDRD (mL/min/1.73 m2)50.8 (46.0–55.6)51.4 (47.0–55.8)0.82
Results of echocardiography
 ESD (mm)30.2 (28.8–31.5)29.3 (28.1–30.6)0.35
 EDD (mm)50.6 (48.5–52.6)48.5 (47.3–49.7)0.008
 IVS (mm)12.5 (11.8–13.2)11.9 (11.5–12.3)0.09
 PW (mm)11.4 (11.0–11.8)10.5 (10.1–12.8)<0.001
 LVM (g)297 (269–324)244 (228–260)<0.001
 RWT ≥ 0.42 (n (%))43 (64.2)60 (63.2)0.97
 LVM indexed for BSA (g/m2)152 (139–165)130 (121–138)0.002
 LVM indexed for height2.7 (g/m2.7)69.6 (63.3–76.0)59.3 (55.5–63.1)0.003
Other measurements
 IMT (mm)0.67 (0.63–0.72)0.69 (0.65–0.72)0.53
 PWV (m/s)13.0 (11.8–14.1)12.4 (11.2–13.5)0.48

Data shown as means 95% CI or frequencies. BMI: body mass index, BSA: body surface area, MACE: major adverse cardiac events, eGFR-MDRD: estimated glomerular filtration rate based on Modification of Diet in Renal Disease Study formula, ESD: left ventricular end-systolic diameter, EDD: left ventricular end-diastolic diameter, IVS: intraventricular septal thickness, PW: posterior wall thickness, LVM: left ventricular mass, RWT: relative wall thickness, IMT: intima-media thickness, and PWV: pulse wave velocity.