Research Article
Fenugreek Seed Extract Inhibit Fat Accumulation and Ameliorates Dyslipidemia in High Fat Diet-Induced Obese Rats
Figure 2
Effect of aqueous extract of Trigonella foenum-graecum (AqE-TFG) on hepatic histopathological changes in high fat diet- (HFD-) induced obese rats. Group 1 (a): NPD control, showing normal liver architecture and hepatocytes; Group 2 (b): HFD control, showing fatty degeneration and greater hepatic lipid accumulation; Group 3 (c): HFD + AqE-TFG (0.5 g/kg, b.w.), showing mild congestion, no fatty changes, and less hepatic lipid accumulation; Group 4 (d): HFD + AqE-TFG (1.0 g/kg, b.w.), showing no fatty changes and considerably lower hepatic lipid accumulation; Group 5 (e): HFD + orlistat (10 mg/kg, b.w.), showing no fatty changes with lower hepatic lipid accumulation.
