Fenugreek Seed Extract Inhibit Fat Accumulation and Ameliorates Dyslipidemia in High Fat Diet-Induced Obese Rats

Table 6

Effect of aqueous extract of Trigonella foenum-graecum (AqE-TFG) on serum lipid levels in high fat diet (HFD)-induced obese rats.

Groups	TC (mg/dL)	TG (mg/dL)	HDL-C (mg/dL)	LDL-C (mg/dL)	VLDL-C (mg/dL)	AI	CRI
Normal control	99.07±2.84	68.32±3.56	32.65±2.25	52.76±4.26	13.66±0.71	0.32±0.03	3.22±0.30
HFD control	156.36±4.00^##	148.90±5.29^##	20.19±1.95^##	106.38±5.45^##	29.78±1.06^##	0.89±0.05^##	8.70±0.79^##
HFD + AqE-TFG (0.5 g/kg)	133.77±2.45^∗∗	103.47±4.70^∗∗	29.84±1.62^∗∗	83.24±2.99^∗∗	20.69±0.94^∗∗	0.54±0.04^∗∗	4.68±0.36^∗∗
HFD + AqE-TFG (1 g/kg)	118.54±3.20^∗∗	83.15±3.86^∗∗	32.91±1.56^∗∗	70.20±4.04^∗∗	16.43±0.77^∗∗	0.43±0.03^∗∗	3.85±0.27^∗∗
HFD + Orlistat (10 mg/kg)	112.78±4.32^∗∗	76.02±4.93^∗∗	33.74±2.18^∗∗	63.84±5.42^∗∗	15.21±0.98^∗∗	0.36±0.05^∗∗	3.64±0.45^∗∗

Results are expressed as mean ± S.E.M. (𝑛=10); ^##𝑃<0.01 compared to normal control; ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared to HFD control.