Body Mass Index and Comorbidities in Adult Severe Asthmatics
Table 1
Demographic characteristics of patients.
Normal weight
Overweight
Obese
value
No.
42
36
24
Body mass index (median and IQR)
22.7 (20.6–23.7)
27.5 (26.4–28.6)
32.3 (30.8–35.3)
<
Age (yrs, mean ± SD)
0.32**
Gender (males, %)
35.4
61.1
33.3
Optimal asthma control (%)
71.4
28.6
0.0
Mean ACQ score (median and IQR)
2.4 (1.3–3.3)
2.0 (1.1–3.3)
3.3 (3.0–3.7)
No. of exacerbation in the last year (median and IQR)
2 (1–3)
2 (1–3)
3 (2–5)
FEV1 (% of predicted, mean ± SD)
0.09**
FVC (% of predicted, mean ± SD)
0.06**
FEV1/FVC (absolute %, mean ± SD)
0.85**
Asthma duration (yrs, median and IQR)
27.5 (21.0–37.0)
26.0 (10.0–37.5)
26.5 (19.0–40.0)
0.69*
Hospitalization for asthma ever (%)
81.0
8.33
75.0
0.72***
Intensive Care Unit for asthma ever (%)
28.6
27.8
33.3
0.89***
OCS in the previous year for asthma (%)
50.0
72.2
79.2
LABA use in the previous year (%)
69.0
83.3
95.8
Aspirine intolerance (%)
14.3
13.9
4.2
0.42***
Antidepressant use (%)
7.1
8.3
4.2
0.82***
Antisthaminic use (%)
64.3
52.8
75.0
0.21***
IQR: interquartile range; ACQ: Asthma Control Questionnaire, Juniper scores; OCS: oral corticosteroids; LABA: long-acting -agonists. Statistical significance among groups was evaluated by *Kruskall-Wallis test, **analysis of variance, and *** test.