The Double-Edged Sword in Pathogenic Trypanosomatids: The Pivotal Role of Mitochondria in Oxidative Stress and Bioenergetics

Figure 3

Common drug effects on the pathogenic trypanosomatid mitochondrion. Treatment with a naphthoquinone leads to mitochondrial swelling (asterisk) and the appearance of concentric membranar structures inside the organelle (arrows). K: typical morphology of the kDNA network. Bar: 200 nm.