Impact of Blood Type, Functional Polymorphism (T-1676C) of the COX-1 Gene Promoter and Clinical Factors on the Development of Peptic Ulcer during Cardiovascular Prophylaxis with Low-Dose Aspirin

Table 3

Multivariate analysis for clinical and genetic factors related to the development of peptic ulcer in aspirin users.

Clinical factor	Coefficient	Standard error	Odds ratio (95% CI)	value
Advanced age	1.248	0.464	3.1 (1.4–8.6)	0.007
Peptic ulcer history	3.320	0.576	27.6 (8.9–85.5)	<0.001
Nonaspirin NSAID use	1.154	0.525	2.9 (1.1–8.0)	0.045
Blood type O	0.751	0.351	2.1 (1.1–4.2)	0.032