Genistein Induces Deleterious Effects during Its Acute Exposure in Swiss Mice
Figure 2
Histological examination of liver sections: photomicrograph of transverse sections of mice liver. (a) Group I: vehicle treated control, (b) Group II: 125 mg/kg, (c) Group III: 250 mg/kg, (d) Group IV: 500 mg/kg, and (e) Group V: 1000 mg/kg. Hydropic changes and degeneration of cytoplasm within hepatocytes were observed in Group IV 500 mg/kg and Group V 1000 mg/kg genistein treated animals. Arrows indicate the degenerated hepatocytes in 500 and 1000 mg/kg genistein treated groups.
