Three-Dimensional In Vitro Models of Granuloma to Study Bacteria-Host Interactions, Drug-Susceptibility, and Resuscitation of Dormant Mycobacteria
Figure 1
Phase contrast images showing the presence of in vitro granuloma-like aggregates after the infection of bovine PBMCs with the bovine K10 strain of M. avium subsp. paratuberculosis at MOI (bacteria : cells) of 1 : 16 (a) and 1 : 8 ((b) and (c)). Original magnification is 10x. Uninfected cells show an absence of granuloma formation (d).
