Application of Molecular Modeling to Urokinase Inhibitors Development

Table 3

Adjustment coefficients of formula (1), determined using the GFIT program GFIT and the training set of 50 uPA-ligand complexes.

𝑘1	𝑘2	𝑘3	𝑘4	𝑘5	𝑘6	𝑘7
0.0292	0.1295	0.2437	−0.0438	0.4958	0.2597	0.0393