Application of Molecular Modeling to Urokinase Inhibitors Development

Table 5

Adjustment coefficients of formula (1), determined using the GFIT program GFIT and the training set of 88 uPA-ligand complexes.

𝑘1	𝑘2	𝑘3	𝑘4	𝑘5	𝑘6	𝑘7
0.0387	0.1387	0.1162	−0.0188	0.1081	0.0504	0.0322