Application of Molecular Modeling to Urokinase Inhibitors Development

Table 6

Comparison of correlation coefficients and numbers of false positives and false negative results (a total of 88 complexes) for the SOL program and the DISCORE program trained by 88 uPA-ligand complexes.

	Correlation coefficient	Number of false positives	Number of false negative
SOL docking	0.35	26 of 88	7 of 88
DISCORE postprocessing (training set)	0.59	10 of 88	8 of 88