Activation of the AT1R/HIF-1α/ACE Axis Mediates Angiotensin II-Induced VEGF Synthesis in Mesenchymal Stem Cells

Figure 4

Ang II degradation and formation. Ang II concentration was determined by radioimmunoassay. Exogenous Ang II (100 nM) was added to the culture medium at time 0. Concentrations were determined at 1, 3, 6, 9, 15, 21, 27, and 33 h. . , 21 h versus 3, 6, 9, 15 h. The concentration of Ang II in untreated MSC culture medium was also tested as the physiological concentration. .