Research Article
Inference of SNP-Gene Regulatory Networks by Integrating Gene Expressions and Genetic Perturbations
Table 1
TPR and FDR of SML, IAL1, and IAL2.
| | | TPR | FDR | SML | IAL1 | IAL2 | SML | IAL1 | IAL2 |
| 100 | 10 | 0.9888 | 1.0000 | 0.9742 | 0.0860 | 0 | 0.0104 | 20 | 0.9980 | 1.0000 | 0.9448 | 0.0503 | 0 | 0.0292 | 30 | 0.9951 | 1.0000 | 0.8936 | 0.0364 | 0 | 0.0754 |
| 500 | 10 | 0.9967 | 1.0000 | 1.0000 | 0.0704 | 0 | 0 | 20 | 0.9850 | 1.0000 | 0.9436 | 0.0400 | 0 | 0.0369 | 30 | 1.0000 | 1.0000 | 0.9128 | 0.0016 | 0 | 0.0562 |
|
|
Expected number of edges per node is and 10 replicates of random network are used. N and M indicate the number of samples and genes, respectively.
|