Research Article

A Time-Dose Model to Quantify the Antioxidant Responses of the Oxidative Hemolysis Inhibition Assay (OxHLIA) and Its Extension to Evaluate Other Hemolytic Effectors

Table 4

Parametric estimations and statistic information of the kinetic series of the survival erythrocyte population inhibited by the antioxidant trolox and fitted to the kinetic model (5).

EffectorKinetic parametersStatisticsReparameterization
Trolox  (M) (% Ert) (min) (% Ert/min) (% Ert/min) (min)

0100 ± 1.1568.12 ± 10.034.59 ± 2.480.99922.34 ± 1.012.35 ± 0.8839.92 ± 12.12
25100 ± 1.1586.05 ± 10.636.44 ± 5.170.99932.59 ± 0.982.63 ± 0.4759.87 ± 17.22
50100 ± 1.15102.96 ± 10.748.26 ± 7.730.99842.78 ± 0.752.85 ± 0.6578.16 ± 21.34
75100 ± 1.15117.26 ± 10.5310.14 ± 6.890.99883.00 ± 0.683.09 ± 0.3294.04 ± 18.75
100100 ± 1.15130.76 ± 10.4711.20 ± 6.920.99872.97 ± 0.593.06 ± 0.89107.22 ± 21.24
125100 ± 1.15144.26 ±10.6010.86 ± 8.300.99712.61 ± 0.852.69 ± 0.97117.51 ± 31.25