Research Article

Gene Delivery Potential of Biofunctional Carbonate Apatite Nanoparticles in Lungs

Figure 4

Comparative retardation assay of CO3Ap/pDNA, Lipofectamine/pDNA, and PEI/pDNA. Lane1: 1 kb DNA ladder, Lane 2: 1 μg uncut pDNA, Lane 3: DMEM, Lane 4: CO3Ap, Lane 5: pDNA in DMEM solution, Lane 6: CO3Ap (8 μL)/pDNA; Lane 7: Lipofectamine/pDNA; and Lane 8: PEI/pDNA. The respective formulations were run on 0.8% agarose gel for 45 min at 75 V.
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