Review Article

Analyzing Association of the XRCC3 Gene Polymorphism with Ovarian Cancer Risk

Table 1

Scale for quality assessment.

CriteriaScore

Source of cases
 Population or cancer registry 3
 Mixed (hospital and cancer registry)2
 Hospital1
 Other0
Source of controls
 Population based 3
 Volunteers or Blood bank2
 Hospital based (cancer-free patients) 1
 Not described 0
Specimens of cases for determining genotypes
 Blood or normal tissues 3
 Mixed (blood and archival paraffin blocks)1
 Tumor tissues or exfoliated cells of tissue 0
Hardy-Weinberg equilibrium in controls
 Hardy-Weinberg equilibrium 3
 Hardy-Weinberg disequilibrium 0
Total sample size
 ≥1000 3
 ≥500 and <1000 2
 ≥200 and <5001
 <200 0