Analyzing Association of the XRCC3 Gene Polymorphism with Ovarian Cancer Risk

Table 4

Distribution of XRCC3 rs1799794 genotype among ovarian cancer cases and controls included in the meta-analysis.

First author	Year	Genotypes distribution; (Case source)			Genotypes distribution; (Controls source)			P-HWE; (Controls)	T2T2 versus T1T1		T1T2 versus T1T1		T1T2+T2T2 versus T1T1		T2T2 versus T1T1+T1T2
		T1T1	T1T2	T2T2	T1T1	T1T2	T2T2		OR (95% CI)	𝑃	OR (95% CI)	𝑃	OR (95% CI)	𝑃	OR (95% CI)	𝑃
Auranen [20]	2005	1060	550	48	2551	1188	161	Yes	0.72 [0.52, 1.00]	0.048	1.11 [0.98, 1.26]	0.087	1.07 [0.95, 1.20]	0.29	0.69 [0.50, 0.96]	0.027
Quaye [25]	2009	940	484	37	1505	713	89	Yes	0.67 [0.45, 0.99]	0.04	1.09 [0.94, 1.25]	0.25	1.04 [0.91, 1.19]	0.57	0.65 [0.44, 0.96]	0.027
Total		2000	1034	85	4056	1901	250		0.70 [0.54, 0.90]	0.005	1.10 [1.00, 1.21]	0.04	1.06 [0.96, 1.15]	0.24	0.67 [0.52, 0.87]	0.002
									Test  for; heterogeneity	𝑃=0.77	Test  for; heterogeneity	𝑃=0.83	Test  for; heterogeneity	𝑃=0.78	Test  for; heterogeneity	𝑃=0.80