Analyzing Association of the XRCC3 Gene Polymorphism with Ovarian Cancer Risk

Table 5

Distribution of XRCC3 rs1799796 genotype among ovarian cancer cases and controls included in the meta-analysis.

First author	Year	Genotypes distribution; (Case source)			Genotypes distribution; (Controls source)			P-HWE; (Controls)	T2T2 versus T1T1		T1T2 versus T1T1		T1T2+T2T2 versus T1T1		T2T2 versus T1T1+T1T2
		T1T1	T1T2	T2T2	T1T1	T1T2	T2T2		OR (95% CI)	𝑃	OR (95% CI)	𝑃	OR (95% CI)	𝑃	OR (95% CI)	𝑃
Auranen [20]	2005	769	692	203	1757	1776	433	Yes	1.07 [0.89, 1.29]	0.47	0.89 [0.79, 1.01]	0.062	0.93 [0.83, 1.04]	0.188	1.13 [0.95, 1.35]	0.17
Quaye [25]	2009	676	608	177	1040	1006	253	Yes	1.08 [0.87, 1.33]	0.5	0.93 [0.81, 1.07]	0.31	0.96 [0.84, 1.09]	0.536	1.11 [0.91, 1.37]	0.30
Total		1445	1300	380	2797	2782	686		1.07 [0.93, 1.24]	0.33	0.91 [0.83, 0.99]	0.04	0.94 [0.86, 1.03]	0.16	1.13 [0.98, 1.29]	0.08
									Test  for; heterogeneity	𝑃=0.97	Test  for; heterogeneity	𝑃=0.65	Test  for; heterogeneity	𝑃=0.69	Test  for; heterogeneity	𝑃=0.90