Development of a Stereotaxic Device for Low Impact Implantation of Neural Constructs or Pieces of Neural Tissues into the Mammalian Brain

Figure 1

A midsagittal view of the rat brain highlighting pathway between the substantia nigra (SN) and striatum. This nigrostriatal circuit was used here as a model system to test the potential to place a neural construct along the length of its pathway, as it is contained within the CNS, has certain clinical relevance (i.e., in research on Parkinson’s disease), and is a well-defined, short circuit of the brain.