Microarray-Based RNA Profiling of Breast Cancer: Batch Effect Removal Improves Cross-Platform Consistency

Figure 5

Density plot of ESR1 gene expression levels and receiver operating characteristic (ROC) curves generated from samples with available immunohistochemical data, measured on the Agilent platform ((a) and (b)), 29K (no adjustments) ((c) and (d)), 29K (intraplatform adj.) and the 29K platform ((f) and (g)). Scatter plot visualizing the correlation between ESR1 expression levels measured on the Agilent platform compared to 29K unadjusted and intraplatform adjusted measurements, respectively ((e), (h)).

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