Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells
Figure 6
Survival pathways analysis in MDA-MB-231. Immunoblot bar chart showing the expression of p-AKT/AKT ratio (a), Survivin (b), and p-ERK/ERK ratio (c) in on ground control cells, RPM adherent cells, and RPM cell clumps at 24 and 72 hours. Columns and bars represent densitometric quantification of optical density (OD) of specific protein signal normalized with the OD values of the GAPDH served as loading control. Each column represents the mean value ± SD of three independent experiments. ; versus on ground control; ; versus RPM adherent cells by ANOVA followed by Bonferroni post-test.
